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Radiance with Cannabis | Research

Updated: Aug 23, 2024

Cannabis and your skin, a path to homeostasis

Here's a Comprehensive list of all the research into how cannabis - specifically the cannabinoids CBD, CBG, and THC, can support renewal of the skin, psyche, and spirit by reducing the harmful effects of stress and supporting the body's natural ability to renew and rejuvenate:


Cannabinoids and the Endocannabinoid System (ECS): CBD, CBG, and THC interact with the body's endocannabinoid system, which plays a crucial role in maintaining homeostasis. The ECS is involved in regulating various physiological processes, including stress response, mood, pain perception, and inflammation.






The Science: Cannabis and Skin

Cannabis interacts with the skin primarily through the endocannabinoid system (ECS), specifically via CB1 and CB2 receptors present in various skin cells. When applied topically, cannabinoids can produce beneficial effects without causing psychoactive reactions. This means that cannabis-based skincare products can soothe and treat the skin without making the user feel "high."


The skin's ECS plays a crucial role in maintaining skin homeostasis, including regulating cell growth, differentiation, and immune responses. Here's how cannabinoids may help with specific skin issues:


Adult Acne: Cannabinoids, particularly CBD, have shown potential in treating adult acne by:

  • Reducing sebum production through interaction with sebocytes

  • Decreasing inflammation via CB2 receptor activation

  • Exhibiting antimicrobial properties against acne-causing bacteria

Eczema: Cannabis may help manage eczema symptoms through:

  • Anti-inflammatory effects, reducing redness and itching

  • Modulation of skin barrier function

  • Potential antimicrobial activity against Staphylococcus aureus, a common aggravator of eczema

Hyper Dryness: Cannabinoids can aid in managing extremely dry skin by:

  • Regulating skin cell proliferation and differentiation

  • Enhancing skin barrier function to reduce transepidermal water loss

  • Modulating the production of skin lipids

Anti-Aging: The anti-aging potential of cannabis stems from its ability to:

  • Act as a potent antioxidant, protecting against free radical damage

  • Reduce inflammation, a key factor in skin aging

  • Potentially stimulate collagen production through interaction with fibroblasts


These effects are primarily mediated through the interaction of cannabinoids with CB1 and CB2 receptors in the skin, as well as other mechanisms such as activation of TRPV1 channels and PPARγ receptors. The non-psychoactive nature of topical cannabis application makes it a promising option for various skin conditions, offering therapeutic benefits without systemic effects.

Cannabis shows promising anecdotal evidence in supporting natural beauty. For targeted skincare, topical applications of CBD-rich products can provide localized benefits. For overall beauty support, a combination of CBN for sleep and CBG for inflammation, either through tinctures or edibles, may help promote that coveted inner glow.


Remember, true beauty comes from within, and a holistic approach that includes proper nutrition, hydration, rest, and stress management is key. Cannabis can be a valuable tool in your beauty box, helping you nurture your natural radiance from the inside out.



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